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Moving Prenatal Screening and Liquid Biopsy Forward

Shifting the Paradigm of Prenatal Screening

The name of our non-invasive prenatal test (NIPT) is appropriately called “UNITY” as it brings together fetal screening for aneuploidies and recessive conditions. It also represents uniting pregnant patients in more equitable care.

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UNITY Screen™ is the only commercially available non-invasive prenatal screen that assesses fetal risk for aneuploidies, recessive conditions, and fetal antigens from a maternal blood draw at 10+ weeks into pregnancy. We are able to quantify the tiny DNA changes floating in cell-free DNA using our molecular counting technology.

UNITY does not require a paternal blood sample to assess fetal risk, supporting more equitable care and enabling more pregnancies at risk to be affected with recessive conditions to be identified early in pregnancy as compared to traditional carrier screening.

Learn More About Unity

Uncovering What’s Possible for Liquid Biopsy

Northstar Select™ and Northstar Response™ are liquid biopsy tests are now available for commercial use. Learn more on the Northstar product website.

Therapy Selection

The Northstar Select™ provides a prioritized list of mutations that are present in the tumor. The types of mutations detected include deletions, insertions, and point-mutations. At the same time, it helps rule-in / rule-out relationship of mutations to drugs and provides an accurate read on the covered genes.

Details

  • Broad genomic coverage
  • Low limit of detection
Learn More About Northstar Select
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Therapy Response

The Northstar Response™ provides longitudinal determination of cancer burden via methylation assessment.

Details

  • Multi cancer methylation signature (nucleotides are methylated in specific locations in cancers)
  • Quantification of changes in tumor burden enabled by our molecular counting technology
Learn More About Northstar Response
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News & Media

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Press Releases

BillionToOne Launches Expanded Panel for UNITY Fetal Risk™ Screen, Setting New Standard in Prenatal Testing

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Press Releases

BillionToOne Expands Executive Team with Dr. Haywood Brown as Chief Medical Officer, Prenatal

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Media Coverage

The San Francisco Business Times 40 Under 40 class of 2025

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Media Coverage

Indianapolis family aims to help expecting parents fight disease affecting tens of thousands of Americans

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Press Releases

BillionToOne Announces Medicare Coverage for Northstar Select®

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Media Coverage

Medicare Covering BillionToOne Northstar Select Cancer Liquid Biopsy Test

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Press Releases

BillionToOne Celebrates Major Milestone: 1 Million UNITY Tests

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Media Coverage

Methylation Monitoring Predicts Pan-Cancer Outcomes

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Media Coverage

Forbes: 2025 Best Startup Employers

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Press Releases

BillionToOne’s Northstar Response® Validated in New Peer-Reviewed Study, Building on Previous Clinical Research

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