Billion To One

We are ONE team,
working towards ONE goal to

detect disease

ONE molecule at a time.

Closeup of BTO lab equipment and an animation showing a grid of letters A T C and G with the focus moving to different letters in the grid

One in a
Few Billion

There are three billion letters, three billion nucleotides that make up our genome. Our proprietary technology has the ability to detect and quantify disease at single base-pair resolution. Our name speaks to this unique technology, and we are focused on applying it to various disease states to help more patients.

Mission, Vision, Values

At the Forefront of
Disease Detection

woman working in a lab

Our proprietary Quantitative Counting Templates, or QCTs™, power our ability to detect and measure tiny and sparse disease-related DNA fragments, or molecules, at the single base-pair level. Several common and severe recessive conditions screened for prenatally can be caused by single-base pair alterations.
Our QCT technology enables quantifying these tiny variations using cell-free DNA. We believe this quantification will open the door to exponential improvements in prenatal screening, liquid biopsy, and beyond.

Moving Prenatal Screening and Oncology Testing Forward

Prenatal closeup on pregnant woman's stomach with her hands lovingly held above and below her belly.

We assess fetal risk for recessive conditions and aneuploidies from maternal blood.
UNITY Screen™ includes a carrier screen as well as a single-gene (for recessive conditions) and aneuploidy NIPT and only requires a maternal blood draw at 10+ weeks to assess fetal risk. No paternal sample needed.

Explore Prenatal
Oncology gloved hand holding a test tube with blood

Northstar Select™ and Northstar Response™ are now available for commercial use.
Northstar Select™ helps determine the most appropriate first line therapy, and Northstar Response™ helps monitor if the therapy is working.

Explore Oncology

Coupling Careers with Great Culture

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“BillionToOne’s leadership values growth of the company’s employees and equality among peers.”

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“I love BillionToOne’s culture, everyone is so welcoming and always open to lend a helping hand.”

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“We have a very strong culture of cross-departmental teamwork. Everyone here cares about making an impact!”

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“I love being able to introduce the latest and greatest technology to Women’s Health providers that will improve their knowledge on each pregnancy and give babies the best shot at healthy beginnings!”

Coupling Careers with Great Culture

What unites our team and drives us forward is one goal of making molecular testing more accurate, efficient, and accessible to all. This special group of bright and talented people is improving healthcare. If this appeals to you, consider joining us.

Leading with Passion and Purpose

Co-founders Oguzhan Atay, Ph.D., and David Tsao, Ph.D., and our team of engineers, scientists, and industry experts care deeply about every sample that comes into our lab.

Collage of three photos: headshots of the two founders and one of a man and woman at a whiteboard

News & Media

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Media Coverage

BillionToOne named the Diagnostics Company of the Year by BioTech Breakthrough Awards

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Press Releases

Leading Molecular Diagnostics Company BillionToOne Announces Three Executive Appointments Amid Rapid Growth

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Media Coverage

The Green Room Podcast from Obstetrics & Gynecology-Interview with Jennifer Hoskovec, MS, author of “Cell-Free DNA Analysis for the Determination of Fetal Red Blood Cell Antigen Genotype in Individuals With Alloimmunized Pregnancies.”

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Media Coverage

A Major Addition to Austin’s Life Science Ecosystem with the Expansion of BillionToOne

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Press Releases

Category Defining Molecular Diagnostics Company BillionToOne Further Solidifies its Long-Term Position by Securing $140 Million Non-Dilutive Financing with Oberland Capital

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Press Releases

BillionToOne Announces Green Journal Publication that Underscores the Role of cell-free DNA NIPT for Fetal Red Blood Cell Antigen Genotyping

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Media Coverage

Slice of Healthcare-BillionToOne Raises $130M In Series D Funding Round

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Media Coverage

Genomeweb-BillionToOne Raises $130M in Series D Financing Round

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Media Coverage

Axios-BillionToOne raises $130M at $1B-plus valuation

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Press Releases

Leading Molecular Diagnostics Company BillionToOne Raises $130 Million in Oversubscribed Series D Funding Over $1B+ Valuation

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