Join the mission to make healthcare more intelligent. For everyone.
What is the most challenging global healthcare problem that physics will allow us to solve?


A different kind of “one-percenter”
Our bar is high, not because we seek perfection, but because we seek purpose. We look for teammates who are intrinsically motivated, who hold themselves to the highest standard even when no one is watching. Collaboration here means genuine partnership where 1 + 1 becomes 3. Challenges aren't obstacles — they're invitations to create something better for every patient, every sample, every day. Walk through our halls and you'll feel it: the focus, the energy, the shared commitment to something larger than ourselves. This is what it means to be part of the ONE.
We are on a mission to remove the fear of the unknown.
Each sample represents a patient receiving insights that could change the course of their healthcare journey. Our products detect the most challenging prenatal genetics non-invasively, uncover over 50% more cancer treatment options, and track tumors months earlier than imaging.

“We are at our best when we serve others... Let us be scientists for humanity.”
- Jane Goodall
Our science begins with people. Every act of precision, collaboration, and care advances a shared mission—to bring intelligent, compassionate healthcare to every life we touch.
BillionToOne spaces, designed for breakthrough work
At BillionToOne, innovation happens everywhere — from our state-of-the-art labs to our collaborative creative spaces. We equip every employee, on-site or remote, with cutting-edge tools and technology designed to amplify creativity, precision, and impact.

Headquarters, Lab 2.0 (CLIA + CAP)

Lab 3.0 (CLIA + CAP)

Coming Soon
Benefits and Perks
Growth & Development
Career Growth & Development
Ongoing learning, mentorship, and structured programs to advance your skills.
Post-Baccalaureate CGMBS Training Program
One-year internal program: 35 hrs/week hands-on, 5 hrs/week didactic; CDPH-approved; ASCP prep.
Open, Transparent Culture
Weekly town halls and clear communication across teams.
Compensation & Ownership
Meaningful Equity-Based Compensation
All positions have some variable pay component, which allows employees to generate an increase in pay based on their performance.
401(k) Retirement Plan
Retirement plan with up to a 4% company match and immediate vesting.
Development & Advancement
Performance reviews twice per year to promote multiple opportunities for development and advancement.
On-Campus & Commuter Perks
Transportation & Commuter Support
CarShare access, and WiFi-enabled commuter shuttles connecting BART, Caltrain, and San Francisco.
Complimentary Fitness Centers
Onsite gyms with classes, weights, pools, saunas, climbing walls and more.
Catered Lunches & Stocked Kitchens
Daily catered lunches from local favorites; fully stocked kitchens.
Work Environment
Generous PTO
Paid time off that increases with tenure.
State-of-the-Art Tools & Spaces
Advanced equipment, hardware, and software in cutting-edge labs and collaborative work areas.
Health & Family
Comprehensive Health Coverage
Multiple medical plans; employee premiums 100% on select plans, dependents covered up to 80%. Dental & vision included.
Fertility & Family Support
Supplemental fertility benefits to support every path to family.
Paid Family & Parental Leave
16 weeks of 100% paid time off for eligible employees.







