careers

Join the mission to make healthcare more intelligent. For everyone.

The question that started it all

What is the most challenging global healthcare problem that physics will allow us to solve?

A different kind of “one-percenter”

Our bar is high, not because we seek perfection, but because we seek purpose. We look for teammates who are intrinsically motivated, who hold themselves to the highest standard even when no one is watching. Collaboration here means genuine partnership where 1 + 1 becomes 3. Challenges aren't obstacles — they're invitations to create something better for every patient, every sample, every day. Walk through our halls and you'll feel it: the focus, the energy, the shared commitment to something larger than ourselves. This is what it means to be part of the ONE.

We are on a mission to remove the fear of the unknown.

Each sample represents a patient receiving insights that could change the course of their healthcare journey. Our products detect the most challenging prenatal genetics non-invasively, uncover over 50% more cancer treatment options, and track tumors months earlier than imaging.

Work and Life at BillionToOne

Open, transparent culture

Weekly town halls that keep us connected

Complimentary meals

Delicious meals delivered from favorite local eateries

Onsite gyms

Complimentary on-site gyms membership for employees

Free shuttle service

Free WiFi and service to BART, Caltrain and San Francisco

Spaces that inspire

State-of-the-art labs alongside collaborative, creative spaces

Pet-friendly spaces

Collaborators in all shapes and sizes

“We are at our best when we serve others... Let us be scientists for humanity.”

- Jane Goodall

Our science begins with people. Every act of precision, collaboration, and care advances a shared mission—to bring intelligent, compassionate healthcare to every life we touch.

BillionToOne spaces, designed for breakthrough work

At BillionToOne, innovation happens everywhere — from our state-of-the-art labs to our collaborative creative spaces. We equip every employee, on-site or remote, with cutting-edge tools and technology designed to amplify creativity, precision, and impact.

Menlo Park, CA

Headquarters, Lab 2.0 (CLIA + CAP)

Union City, CA

Lab 3.0 (CLIA + CAP)

Austin, TX

Coming Soon

Benefits and Perks

Growth & Development

  • Career Growth & Development

    Ongoing learning, mentorship, and structured programs to advance your skills.

  • Post-Baccalaureate CGMBS Training Program

    One-year internal program: 35 hrs/week hands-on, 5 hrs/week didactic; CDPH-approved; ASCP prep.

  • Open, Transparent Culture

    Weekly town halls and clear communication across teams.

Compensation & Ownership

  • Meaningful Equity-Based Compensation

    All positions have some variable pay component, which allows employees to generate an increase in pay based on their performance.

  • 401(k) Retirement Plan

    Retirement plan with up to a 4% company match and immediate vesting.

  • Development & Advancement

    Performance reviews twice per year to promote multiple opportunities for development and advancement.

On-Campus & Commuter Perks

  • Transportation & Commuter Support

    CarShare access, and WiFi-enabled commuter shuttles connecting BART, Caltrain, and San Francisco.

  • Complimentary Fitness Centers

    Onsite gyms with classes, weights, pools, saunas, climbing walls and more.

  • Catered Lunches & Stocked Kitchens

    Daily catered lunches from local favorites; fully stocked kitchens.

Work Environment

  • Generous PTO

    Paid time off that increases with tenure.

  • State-of-the-Art Tools & Spaces

    Advanced equipment, hardware, and software in cutting-edge labs and collaborative work areas.

Health & Family

  • Comprehensive Health Coverage

    Multiple medical plans; employee premiums 100% on select plans, dependents covered up to 80%. Dental & vision included.

  • Fertility & Family Support

    Supplemental fertility benefits to support every path to family.

  • Paid Family & Parental Leave

    16 weeks of 100% paid time off for eligible employees.

Growth that starts at our limits

Our mission demands growth from everyone, in every role. Our career programs invest in that growth — developing new talent, skills, and capabilities.